Tic Toc: Revealing the Potential Internal Clocks of Non-photosynthetic Bacteria

☀️🌙 - ☀️🌙 - ☀️🌙 New Paper Alert! 🎉 Our latest research on circadian clocks in purple bacteria has been published in the International Journal of Molecular Sciences as part of the Special Issue Molecular Insights in Circadian Rhythm and Metabolism!

📚 Title: "Diel Cycle Proteomics: Illuminating Molecular Dynamics in Purple Bacteria for Optimized Biotechnological Applications"

📚 Authors: Sabine Matallana-Surget, Augustin Geron, Corentin Decroo, Ruddy Wattiez

🔍Circadian rhythms, characterized by approximately 24-hour cycles, play a pivotal role in enabling various organisms to synchronize their biological activities with daily variations. While ubiquitous in Eukaryotes, circadian clocks remain exclusively characterized in Cyanobacteria among Prokaryotes. These rhythms are regulated by a core oscillator, which is controlled by a cluster of three genes: kaiA, kaiB, and kaiC.

💡 By employing a set of molecular toolkit, including both shotgun and targeted proteomics, as well as qPCR techniques, we delved deep into the molecular dynamics of circadian rhythms in Rhodospirillum rubrum, a purple bacterium. This research deepens our understanding of how purple bacteria respond to light and dark cycles, offering insights into protein dynamics and the expression of circadian clock genes at both transcriptional and translational levels. This study holds potential for optimizing biotechnological applications, paving the way for efficient fuel and plastic bio-production processes.

📖 Dive deeper into the study here